Pesquisa sobre: PRE-B CELL RECEPTORS 
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Descritor Inglês:   Pre-B Cell Receptors 
Descritor Espanhol:   Receptores de Células Precursoras de Linfocitos B 
Descritor Português:   Receptores de Células Precursoras de Linfócitos B 
Sinônimos Inglês:   Cell Receptor, Pre-B
Cell Receptors, Pre-B
Pre B Cell Receptor
Pre B Cell Receptors
Pre-B Cell Receptor
Receptor, Pre-B Cell
Receptors, Pre-B Cell  
Categoria:   D12.776.124.790.651.950.750
D12.776.377.715.548.950.750
D12.776.543.750.705.816.821.750
Definição Inglês:   Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells. 
Nota Histórica Inglês:   2008 
Qualificadores Permitidos Inglês:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Número do Registro:   52788 
Identificador Único:   D054420 

Ocorrência na BVS:
 

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